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Why was phen phen taken off the market?

The FDA ordered fenfluramine and dexfenfluramine off the market in September 1997 after those drugs were linked to heart valve problems. Fenfluramine was one of the ingredients in "fen-phen," and dexfenfluramine is closely related to fenfluramine.

What can you do for a saggy stomach?
What can you do for a saggy stomach?

7 Ways to Eliminate Loose Stomach Skin Add Exercise to Your Routine. At-home treatment options are ideal for minor sagging. ... Try Topical Creams...

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How many calories do you burn in a day without exercise?
How many calories do you burn in a day without exercise?

How many calories do I burn without exercise? The average person burns around 1800 calories a day doing absolutely nothing. According to the...

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Nov. 5, 2008 -- Two banned obesity drugs may have lingering effects on the heart, according to a new study. The study shows that heart valve problems linked to the banned obesity drugs fenfluramine and/or dexfenfluramine typically last years after stopping those drugs. The FDA ordered fenfluramine and dexfenfluramine off the market in September 1997 after those drugs were linked to heart valve problems. Fenfluramine was one of the ingredients in "fen-phen," and dexfenfluramine is closely related to fenfluramine. The "phen" in fen-phen refers to a drug called phentermine, which wasn't banned. The new study, published online today in BMC Medicine, shows what happened to the hearts of 5,743 former users of fenfluramine and/or dexfenfluramine. Heart Valve Problems The patients were seen by doctors including Charles Dahl, MD, of the Central Utah Clinic in Provo, Utah, between July 1997 and February 2004. During that time, each patient got an echocardiogram and 1,020 patients got two or more echocardiograms 30 months apart, on average. Dahl's team searched the echocardiograms for signs of blood leaking back through heart valves (regurgitation), and they noted which patients got surgery to correct heart valve problems. When the study started, nearly 20% of the women and almost 12% of the men had at least mild regurgitation through the aortic valve or moderate regurgitation through the mitral valve. Those conditions were more likely in women and people who had used fenfluramine and/or dexfenfluramine for longer periods of time. Follow-up echocardiograms showed that aortic and mitral regurgitation usually stayed about the same or worsened, but improved in some cases. Why would some cases worsen and others improve? That's not clear from the study. But the researchers note that they saw evidence of "early improvement, followed by relative stabilization with only slightly more individuals showing improvement over the longer term as compared to deterioration."

What is better rice or potatoes?
What is better rice or potatoes?

The information gathered leads us to a conclusion that rice, especially brown or parboiled kind (white one with added nutrients) is a better choice...

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What removes fat fast?
What removes fat fast?

The 14 Best Ways to Burn Fat Fast START STRENGTH TRAINING. ... FOLLOW A HIGH-PROTEIN DIET. ... SQUEEZE IN MORE SLEEP. ... ADD VINEGAR TO YOUR DIET....

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What foods will flatten my stomach?

Foods for flat stomach Our absolute top 10 foods for flatter stomachs. There's a lot of buzz at the moment around research into foods that can help you eat your way to a flatter stomach. ... Yogurt. Choose natural, Greek style, unsweetened/flavoured yogurt. ... Quinoa. ... Almonds. ... Beans. ... Eggs. ... Salmon. ... Extra virgin olive oil. More items...

There’s a lot of buzz at the moment around research into foods that can help you eat your way to a flatter stomach.

It’s a tempting proposition when it comes to menu choices, but are the promises of these ‘smart foods’ too good to be true?

The bottom line is that loosing fat from your tummy area and getting a flatter stomach takes a multi-pronged approach. You’ll need an active lifestyle and the right exercise programme to burn calories, strengthen your core and strengthen your abdominal muscles. And you’ll need the right nutritional approach. That means a healthy diet that includes a range of beneficial foods. It also means doing your best to avoid some foods you already know will make the battle for a flatter stomach a tougher one!

Can I lose 5kg in a month?
Can I lose 5kg in a month?

By making some small changes to your daily routine, you can safely lose up to 10 pounds (4.5 kg) in just 1 month, hitting your weight loss goals...

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How much should I walk after Panniculectomy?
How much should I walk after Panniculectomy?

Patronella recommends patients take short walks of 10 minutes, gradually increasing this to one mile, twice daily by days 10 to 14 days after the...

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Does apple burn belly fat?
Does apple burn belly fat?

"Eating an apple a day can do more than keep the doctor away, as they are filled with healthy flavonoids and fibers that could help burn belly...

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Can you build muscles after 70?
Can you build muscles after 70?

“Research shows that, even into your late 80s, your body still has the potential to build muscle mass,” Stacy Schroder, director of wellness at...

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