Photo: Julia Larson

Why does bupropion cause weight loss?

Experts aren't exactly sure how bupropion works to stimulate weight loss. It may act on receptors and neurotransmitters in the brain that affect metabolism and appetite.

ro.co - Wellbutrin: How Effective Is Bupropion for Weight Loss? - Ro.co

How do you get rid of saggy belly skin?

Here are six ways you can tighten loose skin. Firming creams. A good choice for a firming cream is one that contains retinoids, says Dr. ......

Last updated Jan 3, 2018

How do I use cinnamon for weight loss?

All you need is cinnamon and water! cinnamon has metabolism-boosting properties that can help your body burn fat more effectively. cinnamon also...

Last updated Sep 22, 2020

Promotion

See more Disclaimer If you have any medical questions or concerns, please talk to your healthcare provider. The articles on Health Guide are underpinned by peer-reviewed research and information drawn from medical societies and governmental agencies. However, they are not a substitute for professional medical advice, diagnosis, or treatment. If your healthcare provider has prescribed bupropion (brand name Wellbutrin) to you for depression or help with quitting smoking, you might be curious about one of its common side effects: weight loss.

Can Wellbutrin be used on its own as a weight loss medication?

We’ll break down what the science says, how Wellbutrin works, and what you and your healthcare provider should consider before you start taking Wellbutrin as part of a weight loss regimen. Lose 15% of your body weight Ro’s 12-month Body Program helps you lose an average of 15% body weight Learn more

Does Wellbutrin cause weight loss?

It can. Bupropion (the generic form of Wellbutrin) was initially prescribed as an antidepressant. It is the only antidepressant associated with weight loss (Alonso-Pedrero, 2019). Healthcare providers noticed that mostly pleasant side effect, and today bupropion is sometimes prescribed as part of a medication for weight loss (naltrexone/bupropion, brand name Contrave), as well as a stop-smoking aid (brand name Zyban).

As far as the evidence that bupropion by itself causes weight loss:

A 2016 study that analyzed the long-term weight loss effect of various antidepressant medications found that non-smokers who took bupropion lost 7.1 pounds over two years. (This effect was not seen in smokers). Users of the other antidepressants in the study gained weight (Arterburn, 2016). Bupropion seems to be effective for weight-loss maintenance as well. A 2012 study found that obese adults who took bupropion SR (standard release) in 300mg or 400mg doses lost 7.2% and 10% of their body weight, respectively, over 24 weeks and maintained that weight loss at 48 weeks (Anderson, 2012). And a 2019 review of 27 studies on antidepressants and weight gain found that antidepressant use increases body weight by an average of 5%—except bupropion, which is associated with weight loss (Alonso-Pedrero, 2019).

What is Wellbutrin?

Bupropion is a drug known as an NDRI (norepinephrine-dopamine reuptake inhibitor). It prevents the brain from absorbing free-floating norepinephrine (a.k.a. adrenaline) and dopamine (otherwise known as the feel-good hormone). This increases the level of both chemicals in the brain (Huecker, 2020). Experts aren’t exactly sure how bupropion works to stimulate weight loss. It may act on receptors and neurotransmitters in the brain that affect metabolism and appetite.

Bupropion is sold in generic form and under several brand names, including:

Why do most people fail weight loss?

Changes in gene expression may help explain why so many diets fail. Dieting increases stress sensitivity, and stress makes us seek out rewarding...

Last updated May 18, 2021

What happens if you take phentermine for years?

The study found that people who stayed on phentermine longer experienced greater weight loss than those who took the drug for three months or less,...

Last updated Mar 10, 2018

Promotion

Aplenzin

Budeprion SR

Budeprion XL

Buproban

Forfivo XL

Wellbutrin

Wellbutrin SR (see Important Safety Information)

Wellbutrin XL (see Important Safety Information)

Zyban

Bupropion is FDA-approved to treat major depressive disorder (MDD) and seasonal affective disorder (SAD). It is also used to help people quit smoking (smoking cessation).

Are weight loss drugs right for me?

If you’re interested in taking bupropion for weight loss, talk with your healthcare provider about whether a weight loss medication is the right option for you. Healthcare providers consider certain factors before prescribing a weight loss medication. These include the potential benefits of the medication, any possible side effects, your current medical status and medications, your family’s medical history, and cost (NIH, 2016). Healthcare providers generally prescribe weight loss medications for people with a BMI (body mass index) of 30 or higher, which signifies obesity. If your BMI is 27 to 29, healthcare providers may prescribe a weight-loss drug if you’re experiencing health problems related to overweight, such as hypertension (high blood pressure) or type 2 diabetes (NIH, 2016). Your healthcare provider also might determine your overweight or obesity can be best treated with simple lifestyle changes—such as a healthy eating plan, regular exercise, and better sleep—before prescribing medication.

Side effects of bupropion

Bupropion can cause certain side effects. Common side effects associated with bupropion include mental changes (like hostility or agitation), dry mouth, headaches, nausea and vomiting and dizziness, and others (DailyMed, 2018). Serious side effects can include seizures, hallucinations, confusion, hypertension (high blood pressure), and allergic reactions (MedlinePlus, 2018). Seek medical advice immediately if you experience these side effects while taking bupropion. Bupropion can also cause drug interactions with certain other medications, including (DailyMed, 2018):

Monoamine oxidase inhibitors (MAOIs)

Blood thinners

Digoxin

HIV antivirals

Anti-seizure medications

Drugs that increase dopamine levels

Drugs that lower the seizure threshold

This is not a complete list of side effects or drug interactions. If you have questions whether a drug or supplement you’re taking might interact with bupropion, ask your healthcare provider or pharmacist.

Weight loss treatments

If you’re considering a medication to treat obesity, bupropion is one of several options. Other medications include phentermine/topiramate (brand name Qsymia), liraglutide (brand name Saxenda), and bupropion/naltrexone (brand name Contrave). Keep in mind, though, that no weight-loss pill will work magic. Your healthcare provider will recommend a healthy diet and regular exercise in addition to any medication.

ro.co - Wellbutrin: How Effective Is Bupropion for Weight Loss? - Ro.co

Does Cymbalta make you lose weight?

Cymbalta is more likely to cause weight loss than weight gain early in the first 8 to 9 weeks of treatment. A modest weight gain may occur after 8...

Last updated Jul 17, 2019

How much fat does 10000 steps burn?

Some claim that individuals can lose a pound of fat a week just by taking 10,000 steps a day because of the potential to burn 3,500 calories from...

Last updated Sep 27, 2022

Promotion

Does L-carnitine work without exercise?

Yes, L-carnitine works without exercise too because it easily converts the fat into energy. The oxidised fatty acids are used as fuel and it is...

Last updated Oct 17, 2021

Promotion

How do you lose belly fat and stay thick?

Doing cardio and targeted strength-training exercises, plus eating a diet with the right nutrients and calories, will help you build a big booty...

Last updated Mar 26, 2021