What is considered a dietary supplement?

The term "dietary supplement" refers to a wide range of products including vitamins and minerals, herbs and other botanicals, amino acids, enzymes, and more. You can find dietary supplements in many forms, such as pills, gummies, powders, liquids, teas, and bars.

cancer.org - What Are Dietary Supplements? - American Cancer Society

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What Are Dietary Supplements?

How are dietary substances supplements different from medicines?

Dietary supplements don't have the same strict safety and effectiveness requirements that medicines do. In the United States, all the medicines you can buy, even without a prescription, must be proven safe and effective, but dietary supplements do not have to be. All prescription and non-prescription medicines are regulated in the US by the Food and Drug Administration (FDA). But dietary supplements are treated more like special foods. In general, the FDA considers new medicines to be unsafe until they are proven safe in clinical trials. New medicines must go through a lot of testing to prove that they are safe and effective before being approved for use by the FDA. And the FDA must approve any new medicine before it can be legally sold in the US. On the other hand, a dietary supplement can be sold without having to prove it is safe and effective first, as long as the maker doesn't claim it can treat, diagnose, prevent, or cure a disease (in which case the FDA would consider it to be a drug). Supplements cannot contain anything that poses a known risk of illness or injury when used as directed on the label, or with normal use if there are no directions on the label. The FDA can stop a company from selling a supplement if it has been found to be unsafe, but only after the FDA gets reports that the supplement has caused harm.

Regulations for dietary supplements

Although supplements are not required to go through clinical trials, companies that make them are supposed to:

Have data showing the products are safe

Make sure that the details on product labels are truthful

Avoid making false claims

Correctly show what is in the supplement

Companies that make dietary supplements must also follow Good Manufacturing Practices (GMPs). The GMPs state that dietary supplements must:

Be produced in a quality manner

Not contain any contaminants or impurities

Be labeled with the ingredients that are actually in the product

The FDA watches for reports of illness, injury, or reactions to supplements. All supplement makers are supposed to report harmful effects to the FDA. The FDA also wants consumers to report reactions or other problems with supplements. The FDA also watches for products on the market that make false claims or contain ingredients known to not be safe. The federal government can act against companies that make false claims about their products or if the supplements are found to be unsafe.

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Which supplement Cannot be taken together?

Don't use calcium, zinc, or magnesium supplements at the same time. Also, these three minerals are easier on your tummy when you take them with food, so if your doctor recommends them, have them at different meals or snacks.

webmd.com - Supplement Smarts: Best Ways to Take Different Vitamins - WebMD

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National Institutes of Health Office of Dietary Supplements: “Multivitamin/mineral Supplements,” “Vitamin A,” “Daily Values,” “Frequently Asked Questions,” “Vitamin and Mineral Upper Limits -- What You Need to Know,” “Dietary Supplements: What You Need to Know."

UT Southwestern Medical Center: “5 signs you’ve chosen the right multivitamin.”

Cleveland Clinic: “Get Nauseous After Taking Vitamins? 6 Tips to Make Them Easier to Stomach,” “Vitamin B12 Oral.” Harvard Health: “B Vitamins,” “What patients -- and doctors -- need to know about vitamins and supplements.” ConsumerLab.com: “Supplements That Should Be Taken With Food,” “Best Time to Take Multivitamins,” “How to Take Vitamins and Minerals for the Proper Absorption,” “Gummy Vitamin Concerns.”

Linus Pauling Institute: “Vitamin E.”

New England Journal of Medicine: “Drug Effects on the Thyroid.”

Colorado State University Extension: “Dietary Supplements: Vitamins and Minerals.”

Center for Science in the Public Interest: “Don’t Rely on a Gummy Multivitamin If You Can Swallow a Tablet.”

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