What happens when you start taking Ozempic?

webmd.com - Ozempic Pen Injector - Uses, Side Effects, and More - WebMD

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See also Warning section.

Swelling/redness/itching at the injection site, tiredness, nausea, vomiting, diarrhea, or constipation may occur. Nausea usually lessens as you continue to use semaglutide. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: signs of kidney problems (such as change in the amount of urine), vision changes (such as decreased/blurred vision). Get medical help right away if you have any very serious side effects, including: signs of pancreas or gallbladder disease (such as nausea/vomiting that doesn't stop, severe stomach/abdominal pain). Although semaglutide by itself usually does not cause low blood sugar (hypoglycemia), low blood sugar may occur if this drug is prescribed with other diabetes medications. Talk with your doctor or pharmacist about whether the dose(s) of your other diabetes medication(s) needs to be lowered. Drinking large quantities of alcohol, not getting enough calories from food, or doing unusually heavy exercise may also lead to low blood sugar. Symptoms may include sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, headache, or tingling hands/feet. It is a good habit to carry glucose tablets or gel to treat low blood sugar. If you don't have these reliable forms of glucose, rapidly raise your blood sugar by eating a quick source of sugar such as table sugar, honey, candy, or drinking a glass of fruit juice or non-diet soda. Check with your doctor or pharmacist to find out what you should do if you miss a meal. Symptoms of high blood sugar (hyperglycemia) include increased thirst/urination. If these symptoms occur, tell your doctor right away. Your dosage may need to be increased. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

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Can Ozempic harm your kidneys?

Since the half-life of Ozempic is about seven days6, our patient's renal function recovered after four weeks. Luckily, the kidney damage was reversible. Physicians should be aware of such potential rare complications when prescribing GLP-1 agonists and closely monitor renal function after initiation.

endocrinepractice.org - A Rare and Uncommon Side Effect of Semaglutide - Endocrine Practice

Glucagon-like peptide-1(GLP-1) receptor agonists play a significant role in treating type 2 diabetes and obesity. Their extended half-life allows for once-weekly injections1. Semaglutide has cardioprotective and renoprotective effects2 with decreased cardiovascular death rates, nonfatal myocardial infarction, or nonfatal stroke3. SUSTAIN 6 trial, a post hoc analysis that assessed its effects on mean estimated glomerular filtration rate (eGFR), did not show adverse renal outcomes regardless of baseline renal function4. To our knowledge, only two cases5 report acute kidney injury (AKI) that developed on a background of chronic kidney disease after starting semaglutide6. We discuss a patient with normal kidney function who developed AKI after starting Semaglutide.

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