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What happens if you take too much Saxenda?

Too much Saxenda may cause severe nausea and vomiting. If you miss your daily dose of Saxenda, use Saxenda as soon as you remember. Then take your next daily dose as usual on the following day. Do not take an extra dose of Saxenda or increase your dose on the following day to make up for your missed dose.

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Serious side effects may happen in people who take Saxenda, including:

1. Possible thyroid tumors, including cancer. During the drug testing process, the medicine in Saxenda caused rats and mice to develop tumors of the thyroid gland. Some of these tumors were cancers. It is not known if Saxenda will cause thyroid tumors or a type of thyroid cancer called medullary thyroid cancer in people. If medullary thyroid cancer occurs, it may lead to death if not detected and treated early. If you develop tumors or cancer of the thyroid, your thyroid may have to be surgically removed. Before you start taking Saxenda, tell your healthcare provider if you or any of your family members have had thyroid cancer, especially medullary thyroid cancer, or Multiple Endocrine Neoplasia syndrome type 2. Do not take Saxenda if you or any of your family members have medullary thyroid cancer, or if you have Multiple Endocrine Neoplasia syndrome type 2. People with these conditions already have a higher chance of developing medullary thyroid cancer in general and should not take Saxenda. While taking Saxenda, tell your healthcare provider if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. 2. Inflammation of the pancreas (pancreatitis), which may be severe and lead to death. Before taking Saxenda, tell your healthcare provider if you have had:

pancreatitis

stones in your gallbladder (gallstones)

a history of alcoholism

high blood triglyceride levels

These medical conditions can make you more likely to get pancreatitis in general. It is not known if having these conditions will lead to a higher chance of getting pancreatitis while taking Saxenda. Stop taking Saxenda and call your healthcare provider right away if you have pain in your stomach area (abdomen) that is severe and will not go away. The pain may happen with or without vomiting. The pain may be felt going from your abdomen through to your back. This type of pain may be a symptom of pancreatitis. 3. Low blood sugar (hypoglycemia). Your risk for getting low blood sugar is higher if you take Saxenda with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin. In some people, the blood sugar may get so low that they need another person to help them. The dose of your sulfonylurea medicine or insulin may need to be lowered while you use Saxenda. Signs and symptoms of low blood sugar may include:

shakiness

sweating

headache

drowsiness

weakness

dizziness

confusion

irritability

hunger

fast heartbeat

feeling jittery

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Talk to your healthcare provider about how to recognize and treat low blood sugar. Make sure that your family and other people who are around you a lot know how to recognize and treat low blood sugar. 4. Kidney problems (kidney failure). Saxenda may cause nausea, vomiting or diarrhea leading to loss of fluids (dehydration). Dehydration may cause kidney failure which can lead to the need for dialysis. This can happen in people who have never had kidney problems before. Drinking plenty of fluids may reduce your chance of dehydration. Call your healthcare provider right away if you have nausea, vomiting, or diarrhea that does not go away, or if you cannot drink liquids by mouth. 5. Serious allergic reactions. Serious allergic reactions can happen with Saxenda. Stop using Saxenda, and get medical help right away if you have any symptom of a serious allergic reaction. Symptoms of a serious allergic reaction may include:

swelling of your face, lips, tongue, or throat

fainting or feeling dizzy

very rapid heartbeat

problems breathing or swallowing

severe rash or itching

6. Gallbladder problems. Saxenda may cause gallbladder problems including gallstones. Some gallbladder problems need surgery. Call your healthcare provider if you have any of the following symptoms: pain in your upper stomach (abdomen)

fever

yellowing of your skin or eyes (jaundice)

clay-colored stools

7. Heart Rate Increase. Saxenda can increase your heart rate while you are at rest. Your healthcare provider should check your heart rate while you take Saxenda. Tell your healthcare provider if you feel your heart racing or pounding in your chest and it lasts for several minutes when taking Saxenda. 8. Depression or thoughts of suicide. You should pay attention to any mental changes, especially sudden changes, in your mood, behaviors, thoughts, or feelings. Call your healthcare provider right away if you have any mental changes that are new, worse, or worry you.

Do not use Saxenda if:

you or any of your family members have a history of medullary thyroid cancer. you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). This is a disease where people have tumors in more than one gland in their body. you are allergic to Saxenda or any of the ingredients in Saxenda. Symptoms of a serious allergic reaction may include: swelling of your face, lips, tongue, or throat fainting or feeling dizzy very rapid heartbeat problems breathing or swallowing severe rash or itching Talk with your healthcare provider if you are not sure if you have any of these conditions.

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