Tropical Weight Loss
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Share on Pinterest Have researchers found a new way to prevent obesity and its associated conditions? A study by Cincinnati Children's Hospital Medical Center in Ohio reveals that a protein called Argonaute 2 (AGO2) controls how energy is made and used in the liver.
How to Lose 20 Pounds as Fast as Possible Count calories. ... Drink more water. ... Increase your protein intake. ... Reduce your refined carb...
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How to Tighten Loose Skin After Weight Loss Using Resistance Training. Some natural remedies can tighten loose skin after weight loss. ... Using...
Read More »Blocking a protein in the liver can prevent obesity and its related diseases — such as type 2 diabetes and fatty liver — in mice, according to new research. Share on Pinterest Have researchers found a new way to prevent obesity and its associated conditions? A study by Cincinnati Children’s Hospital Medical Center in Ohio reveals that a protein called Argonaute 2 (AGO2) controls how energy is made and used in the liver. It does this by silencing RNA, a molecule that carries genetic instructions held in the DNA blueprints in the cell’s nucleus to the cell’s protein-making machinery. The scientists revealed that, by silencing RNA, AGO2 slows metabolism in the liver and the organ’s “ability to process a high-fat diet.” However, when they deleted AGO2 in the livers of mice on a high-fat diet, the mice did not become obese and did not develop type 2 diabetes and fatty liver disease. Fatty liver disease — or, more accurately, nonalcoholic fatty liver disease — is a condition in which fat builds up in the liver. It can severely harm the organ, whose main job is to clean and detoxify blood. Vicious cycle in disrupted energy metabolism The findings suggest that RNA silencing by AGO2 links two important processes: control of energy supply, and the production of proteins inside cells. “This mechanism,” note the investigators in a recently published Nature Communications paper on their work, “may be the core of a vicious cycle in disrupted energy metabolism in the obese liver.” The team identified AGO2 after screening and analyzing the behavior of genes and the associated proteins that they target in the liver. They examined the effect of deleting proteins that play a key role in liver metabolism in normal and genetically engineered mice that were fed on high-fat diets. Senior study author Takahisa Nakamura, an assistant professor in the Department of Pediatrics at Cincinnati Children’s Hospital, warns that the science is “still basic,” and that it is too early to say how it might translate into new treatments. There might be important implications, however, for the treatment of “chronic metabolic disorders like diabetes, fatty liver diseases, and other obesity-associated illnesses,” he notes. What they have achieved so far, Nakamura suggests, should help them search for potential new treatments that target obesity and associated diseases by altering energy balance in the liver. Further work will involve the confirmation of these findings in “laboratory models” and the development of an experimental AGO2 blocker for clinical testing in humans.
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Phentermine 15 mg twice a day is sometimes used by people who have a problem with snacking. This is legal because the combined dose of 15 mg and 15...
Read More »To avoid weight gain, experts recommend adding 2,000 steps a day to your routine, doing strength training two to three times a week, and shaving 100 calories from your diet each day. Here are some simple ways to shave 100 calories a day: Eat two fewer cookies.
Your favorite pair of pants once zipped easily, but lately you can barely get them over your hips. Sound familiar? Most adults experience the dreaded "weight creep," where the numbers on the scale gradually increase -- and before you know it, you're 10 pounds heavier. But it’s not inevitable. Simply by making a few gradual lifestyle changes, experts say, you can stop gaining weight and even drop some pounds.
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