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Is there a generic alternative to Ozempic?

Has a generic version of Ozempic been approved? No. There is currently no therapeutically equivalent version of Ozempic available in the United States.

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Last updated on Jan 11, 2023.

Ozempic is a brand name of semaglutide, approved by the FDA in the following formulation(s): No. There is currently no therapeutically equivalent version of Ozempic available in the United States. Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Ozempic. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: Generic Drug FAQ.

Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.

Syringe device with a dose limiting mechanism and an additional safety mechanism

Patent 10,220,155

Issued: March 5, 2019

Assignee(s): Novo Nordisk A/S

A syringe device for ejecting a dose of a medicament, the syringe device comprising: a dose limiting mechanism arranged to interact with a dose ejecting mechanism to prevent ejection of a dose exceeding a set dose, and a safety mechanism, which is arranged such with respect to the dose ejecting mechanism that, if the dose limiting mechanism fails, the safety mechanism prevents ejection of a dose exceeding the set dose. Patent expiration dates: July 17, 2026

✓ Drug product

Use of long-acting GLP-1 peptides

Patent 10,335,462

Issued: July 2, 2019

Assignee(s): Novo Nordisk A/S

The invention relates to use of long-acting GLP-1 peptides in certain dosage regimes for the treatment of type 2 diabetes, obesity, etc. Patent expiration dates: June 21, 2033

June 21, 2033

Patent 10,357,616

Patent expiration dates: January 20, 2026

✓ Drug product

Patent 10,376,652

Patent expiration dates: January 20, 2026

✓ Drug product

Patent 11,097,063

Patent expiration dates: July 17, 2026

✓ Drug product

Patent 11,311,679

Patent expiration dates: January 20, 2026

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Patent 11,446,443

Patent expiration dates: October 20, 2025

✓ Drug product

Automatic injection device with reset feature

Patent 6,899,699

Issued: May 31, 2005

Inventor(s): Enggaard; Christian

Assignee(s): Novo Nordisk A/S

The present invention relates to a dose setting and expelling device comprising a drive member and a dose setting mechanism which simultaneously sets a given dose and stores the energy necessary for a subsequently driving the drive member in order to expel a dose of medicine from an injection device. According to the invention the dose setting mechanism allows adjustment in both directions, such that a given set dose can be reduced or cancelled by reversing the input motion, typically by rotating a setting member backwardly, this in contrast to the known devices which either requires an additional release mechanism or which cannot be reversed at all. Patent expiration dates: January 2, 2022

✓ Drug product

Needle mounting system and a method for mounting a needle assembly

Patent 7,762,994

Issued: July 27, 2010

Inventor(s): Klint; Henrik Sonderskov & Radmer; Jim & Smedegaard; Jorgen K & Nielsen; Jan Frank & Jensen; Peter Moller & Jensen; Jens Moller

Assignee(s): Novo Nordisk A/S

A needle mounting system and methods for mounting a needle assembly on a needle mount are disclosed. The needle mounting system includes a needle hub having protrusions extending radially inward. A needle mount has a plurality of slots to receive the protrusions. The slots have a first portion that defines a passageway substantially parallel to a longitudinal axis of the needle mount and a second portion substantially perpendicular to the axis. The needle hub and mount provide a method wherein a needle assembly may be mounted on an injection device without completely rotating the needle hub relative to the needle mount. Patent expiration dates: May 23, 2024

✓ Drug product

Propylene glycol-containing peptide formulations which are optimal for production and for use in injection devices

Patent 8,114,833

Issued: February 14, 2012

Inventor(s): Pedersen; Tina Bjeldskov & Bonde; Claude & Engelund; Dorthe Kot

Assignee(s): Novo Nordisk A/S

The present invention relates to pharmaceutical formulations comprising a peptide and propylene glycol, to methods of preparing such formulations, and to uses of such formulations in the treatment of diseases and conditions for which use of the peptide contained in such formulations is indicated. The present invention further relates to methods for reducing the clogging of injection devices by a peptide formulation and for reducing deposits on production equipment during production of a peptide formulation. Patent expiration dates: August 13, 2025

✓ Drug product

Acylated GLP-1 compounds

Patent 8,129,343

Issued: March 6, 2012

Inventor(s): Lau; Jesper & Bloch; Paw & Hansen; Thomas Kruse

Assignee(s): Novo Nordisk A/S

Protracted GLP-1 compounds and therapeutic uses thereof. Patent expiration dates: December 5, 2031

December 5, 2031

December 5, 2031

Acylated GLP-1 compounds

Patent 8,536,122

Issued: September 17, 2013

Assignee(s): Novo Nordisk A/S

Protracted GLP-1 compounds and therapeutic uses thereof. Patent expiration dates: March 20, 2026

March 20, 2026

March 20, 2026

Needle mounting system and a method for mounting a needle assembly

Patent 8,579,869

Issued: November 12, 2013

Assignee(s): Novo Nordisk A/S

A needle mounting system and methods for mounting a needle assembly on a needle mount are disclosed. The needle mounting system includes a needle hub having protrusions extending radially inward. A needle mount has a plurality of slots to receive the protrusions. The slots have a first portion that defines a passageway substantially parallel to a longitudinal axis of the needle mount and a second portion substantially perpendicular to the axis. The needle hub and mount provide a method wherein a needle assembly may be mounted on an injection device without completely rotating the needle hub relative to the needle mount. Patent expiration dates: June 30, 2023

✓ Drug product

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Automatic injection device with reset feature

Patent 8,672,898

Issued: March 18, 2014

Assignee(s): Novo Nordisk A/S

The present invention relates to a dose setting and expelling device comprising a drive member and a dose setting mechanism which simultaneously sets a given dose and stores the energy necessary for a subsequently driving the drive member in order to expel a dose of medicine from an injection device. According to the invention the dose setting mechanism allows adjustment in both directions, such that a given set dose can be reduced or cancelled by reversing the input motion, typically by rotating a setting member backwardly, this in contrast to the known devices which either requires an additional release mechanism or which cannot be reversed at all. Patent expiration dates: January 2, 2022

✓ Drug product

Injection device with torsion spring and rotatable display

Patent 8,684,969

Issued: April 1, 2014

Assignee(s): Novo Nordisk A/S

The present invention relates to an injection device comprising a torsion spring operatively connected to a dose setting member being adapted to set a dose to be ejected from the injection device. A rotatably mounted display member adapted to display the dose to be ejected in accordance with a setting of the dose setting member is also provided. The rotatably mounted display member is adapted to be rotated over an angle corresponding to at least one revolution of the display member. The display member may be implemented as a dose indicator barrel having numerals arranged along a helical path on an outer surface thereof, or alternatively, as a counting device having two or more display wheels having numerals arranged on an outer surface thereof. Patent expiration dates: October 20, 2025

✓ Drug product

Dose mechanism for an injection device for limiting a dose setting corresponding to the amount of medicament left

Patent 8,920,383

Issued: December 30, 2014

Assignee(s): Novo Nordisk A/S

A mechanism for preventing setting of a dose, which exceeds the amount of a medicament in a reservoir in an injection device. The device comprises a threaded piston rod, a limiter and a driver. The three elements are arranged such that during dose setting, the limiter is moved towards an end-of-contend position, wherein dose setting is limited. The invention comprises an accumulative and a non-accumulative embodiment. The invention further relates to a mechanism for prevention ejection of a dose exceeding the set dose. Patent expiration dates: July 17, 2026

✓ Drug product

Automatic injection device with a top release mechanism

Patent 9,108,002

Issued: August 18, 2015

Assignee(s): Novo Nordisk A/S

The present invention relates to a handheld mechanical injection device by which set doses of a liquid medicament can be injected from a medical reservoir. The medicament is expelled through an injection needle by release of a power reservoir in the device, the power reservoir being fully or partially released by actuation of a user operable release member being positioned at or near an upper end of the injection device, the upper end being that end of the injection device which is opposite the injection needle. Patent expiration dates: January 20, 2026

✓ Drug product

Dial-down mechanism for wind-up pen

Patent 9,132,239

Issued: September 15, 2015

Assignee(s): Novo Nordisk A/S

The present invention relates to a dial-down mechanism for an injection device comprising a torsion spring for assisting injection of a dose of medicament from the injection device, the dial-down mechanism comprising a ratchet arm (21) engaging a ring element (10) and a reset element (30) which acts on a knob located on the periphery of the ratchet arm (21) to move the ratchet arm (21) out of engagement with the ring element (10) in order to allow the set dose to be reduced. Patent expiration dates: February 1, 2032

✓ Drug product

Injection device with an end of dose feedback mechanism

Patent 9,457,154

Issued: October 4, 2016

Assignee(s): Novo Nordisk A/S

An injection device with a dose delivering mechanism being adapted to provide a non-visual, e.g. audible and/or tactile, feedback signal when a set dose has been at least substantially injected. A first and a second part of the injection device are adapted to perform a relative rotational movement with respect to each other. The relative rotational movement causes at least two parts of the injection device to abut or engage, and this abutment or engagement causes the non-visual feedback signal to be generated. A very distinct and precise feedback is provided as compared to prior art axial solutions because the generation of the feedback signal is initiated by the relative rotational movement. Feedback signal may be generated by a change in a rotational velocity of at least one part, e.g. by changing the pitch of a threaded portion or by engaging a non-rotating part and a rotating part, thereby causing the non-rotating part to start rotating. May alternatively be generated by building up and releasing a tension. The injection device is suitable for injecting insulin. Patent expiration dates: September 27, 2027

✓ Drug product

September 29, 2027

✓ Drug product

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Automatic injection device with reset feature

Patent 9,486,588

Issued: November 8, 2016

Assignee(s): Novo Nordisk A/S

The present invention relates to a dose setting and expelling device comprising a drive member and a dose setting mechanism which simultaneously sets a given dose and stores the energy necessary for a subsequently driving the drive member in order to expel a dose of medicine from an injection device. According to the invention the dose setting mechanism allows adjustment in both directions, such that a given set dose can be reduced or cancelled by reversing the input motion, typically by rotating a setting member backwardly, this in contrast to the known devices which either requires an additional release mechanism or which cannot be reversed at all. Patent expiration dates: January 2, 2022

✓ Drug product

Automatic injection device with a top release mechanism

Patent 9,616,180

Issued: April 11, 2017

Assignee(s): Novo Nordisk A/S

The present invention relates to a handheld mechanical injection device by which set doses of a liquid medicament can be injected from a medical reservoir. The medicament is expelled through an injection needle by release of a power reservoir in the device, the power reservoir being fully or partially released by actuation of a user operable release member being positioned at or near an upper end of the injection device, the upper end being that end of the injection device which is opposite the injection needle. Patent expiration dates: January 20, 2026

✓ Drug product

Injection device with torsion spring and rotatable display

Patent 9,687,611

Issued: June 27, 2017

Assignee(s): Novo Nordisk A/S

The present invention relates to an injection device comprising a torsion spring operatively connected to a dose setting member being adapted to set a dose to be ejected from the injection device. A rotatably mounted display member adapted to display the dose to be ejected in accordance with a setting of the dose setting member is also provided. The rotatably mounted display member is adapted to be rotated over an angle corresponding to at least one revolution of the display member. The display member may be implemented as a dose indicator barrel having numerals arranged along a helical path on an outer surface thereof, or alternatively, as a counting device having two or more display wheels having numerals arranged on an outer surface thereof. Patent expiration dates: February 27, 2027

✓ Drug product

Dose mechanism for an injection device for limiting a dose setting corresponding to the amount of medicament left

Patent 9,775,953

Issued: October 3, 2017

Assignee(s): Novo Nordisk A/S

A mechanism for preventing setting of a dose, which exceeds the amount of a medicament in a reservoir in an injection device. The device can contain a threaded piston rod, a limiter and a driver. The three elements can be arranged such that during dose setting, the limiter is moved towards an end-of-content position, wherein dose setting is limited. The invention contains an accumulative and a non-accumulative embodiment. The invention further relates to a mechanism for preventing ejection of a dose exceeding the set dose. Patent expiration dates: July 17, 2026

✓ Drug product

Injection device with an end of dose feedback mechanism

Patent 9,861,757

Issued: January 9, 2018

Assignee(s): Novo Nordisk A/S

An injection device with a dose delivering mechanism being adapted to provide a non-visual, e.g. audible and/or tactile, feedback signal when a set dose has been at least substantially injected. A first and a second part of the injection device are adapted to perform a relative rotational movement with respect to each other. The relative rotational movement causes at least two parts of the injection device to abut or engage, and this abutment or engagement causes the non-visual feedback signal to be generated. A very distinct and precise feedback is provided as compared to prior art axial solutions because the generation of the feedback signal is initiated by the relative rotational movement. Feedback signal may be generated by a change in a rotational velocity of at least one part, e.g. by changing the pitch of a threaded portion or by engaging a non-rotating part and a rotating part, thereby causing the non-rotating part to start rotating. May alternatively be generated by building up and releasing a tension. The injection device is suitable for injecting insulin. Patent expiration dates: January 20, 2026

✓ Drug product

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