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Is Ozempic hard on your kidneys?

The analysis found that significant beneficial effects on kidney function and renal outcomes were seen with Ozempic and Victoza, with fewer people showing a persistent eGFR reduction and people with pre-existing kidney disease achieving significantly slower annual loss of kidney function versus placebo.

Do people gain weight back after Ozempic?
Do people gain weight back after Ozempic?

Recent research published in the journal Diabetes, Obesity and Metabolism indicates that once patients stop using semaglutide drugs like Wegovy and...

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How can a woman become more fertile?
How can a woman become more fertile?

What can I do to promote female fertility? Maintain a healthy weight. Being overweight or significantly underweight can inhibit normal ovulation....

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The analysis found that significant beneficial effects on kidney function and renal outcomes were seen with Ozempic and Victoza, with fewer people showing a persistent eGFR reduction and people with pre-existing kidney disease achieving significantly slower annual loss of kidney function versus placebo. The GLP-1 agonist was found to be non-inferior to placebo in the PIONEER 6 trial, with 3.8% of patients taking it experiencing cardiovascular complications compared to 4.8% of the control group, with an added 50% reduction in death. Mads Krogsgaard Thomsen, executive vice president and chief science officer of Novo Nordisk told PharmaTimes exclusively that “All these investments; the SOUL trial, the FLOW trial, the STEP trial and FOCUS trial - in a matter of a few weeks we have started three major outcome studies which is a really unique situation for one single medicinal product. It’s because we aim to invest heavily in semaglutide, to show that it has all of these possible indications. So, that’s the dream come true for us and for the patients too I believe.” He went on to explain why the drugs are important for this area of significant unmet need, saying: “SGLT-2 inhibitors are doing great things for the kidneys. However, that’s for one class of patients only, and they don’t have any anti-diabetic action because they are dependent on the kidneys filtering, and when they kidneys stop filtering, they stop working. “Even though they can protect the kidneys, they can’t do anything for the diabetic condition when patients have severely impaired renal function. But, Ozempic and Victoza work independently from the kidneys. They are not eliminated by the kidneys and they can even be given to a patient via haemodialysis. “They can be given to patients with any degree of kidney dysfunction or impairment. So, it is a relatively unique situation. Victoza saw a 22% kidney improvement and Ozempic saw 36%, in the LEADER and SUSTAIN 6 trials respectively.” Despite reno protective standard of care recommendations, up to 40% of people with type II diabetes develop chronic kidney disease, but Novo Nordisk are aiming for “semaglutide to be the director of the metabolic orchestra”, and for it to be see as “more of a cardio metabolic renal agent, tackling the whole complex.” Ozempic was approved by the European Commission on 8 February 2018, based on the SUSTAIN programme, a global clinical development programme that comprised eight phase 3a trials, encompassing more than 8,000 adults with type II diabetes. In Europe, approved in 2009, Victoza is indicated for the treatment of adults with insufficiently controlled type II diabetes together with diet and exercise, as monotherapy when metformin is considered inappropriate due to intolerance or contraindications and in addition to other medicinal products for the treatment of diabetes.

How many hours is 10,000 steps?
How many hours is 10,000 steps?

What does 10,000 steps look like? Ten thousand steps equates to about eight kilometres, or an hour and 40 minutes walking, depending on your stride...

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How can I burn 500 calories in 30 minutes?
How can I burn 500 calories in 30 minutes?

12 Best Exercises To Burn 500 Calories In 30 Minutes HIIT (High-Intensity Interval Training) ... Zumba/Dancing. ... Kickboxing. ... Swimming. ......

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Is Saxenda best taken at night?

What time of the day should I use my Saxenda medication? Saxenda can be taken at any time of the day at a time that is convenient for you. For the best results stick to the same time each day.

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Is rice good for weight loss?
Is rice good for weight loss?

In short, white rice appears to be neither detrimental nor favorable for weight loss. However, eating diets high in whole grains like brown rice...

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Can you tone a flabby tummy?
Can you tone a flabby tummy?

In addition to cardio, ab exercises can help you start getting rid of excess belly fat and flatten and tone the stomach area. Mar 17, 2022

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Is it better to sleep with or without your socks on?
Is it better to sleep with or without your socks on?

Wearing socks in bed is the safest way to keep your feet warm overnight. Other methods such as rice socks, a hot water bottle, or a heating blanket...

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What should I do if I can't lose weight?
What should I do if I can't lose weight?

No Matter What I Do I Can't Lose Weight: True Reasons Your Scale Won't Budge And Viable Solutions Get A Good Night's Sleep. Eat High Fiber Foods....

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