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Is it OK to take testosterone shots?

Testosterone injections may be safe for many people when they follow a doctor's instructions. However, research has also linked testosterone therapy with several side effects and possible complications. Possible negative effects of testosterone therapy may include: an increased risk of cardiovascular complications.

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Testosterone injections are hormone treatments. Their primary use is as a treatment for sexual dysfunction in males and postmenopausal symptoms in females with a testosterone deficiency. Transgender men and nonbinary people may also use testosterone injections as part of masculinizing therapy. Testosterone injections are safe for many people, but they can have side effects. The side effects may be different depending on the reason why the person is using the injections. Although testosterone injections can help for low testosterone due to medical conditions, the Food and Drug Administration (FDA) do not recommend using testosterone to treat natural aging-related testosterone changes as it may increase the risk of certain health issues. Keep reading for more information on testosterone injections, including their uses, safety, and potential side effects. Types of testosterone injection Testosterone injections can come in several varieties. These include: testosterone cypionate (Depo-Testosterone)

testosterone enanthate (Xyosted and also available in its generic form)

testosterone undecanoate (Aveed, which is a long acting formulation)

How to use them When a person receives a testosterone injection, the hormone directly enters the body through the muscle. People can choose between two methods: self-administering the injections at home, using a home injection kit to inject the hormone into the thigh having a doctor administer them into the buttocks muscle during a visit to the doctor’s office When having testosterone injections, people will usually visit their doctor every few months for monitoring. Treatments could last for a lifetime or be short-term, depending on the individual’s circumstances. Are they safe? Testosterone injections may be safe for many people when they follow a doctor’s instructions. However, research has also linked testosterone therapy with several side effects and possible complications. Possible negative effects of testosterone therapy may include: an increased risk of cardiovascular complications

worsened symptoms in the lower urinary tract

polycythemia, a rare type of blood cancer

an increased risk of venous thrombosis Some people may have an allergic reaction to testosterone injections. For example, testosterone undecanoate may cause a serious allergic reaction or breathing issues following the injection. Symptoms can include breathing problems, dizziness, and skin rashes. Other forms of testosterone, including testosterone enanthate, may increase blood pressure, which can raise the risk of a stroke or heart attack. People who have had strokes, heart attacks, heart disease, or high blood pressure should make the doctor aware of this before starting testosterone injections, as they may have a higher risk of complications. If someone experiences any of the following symptoms after a testosterone injection, they should seek emergency medical attention: shortness of breath

slow or difficult speech

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chest pain

weakness or numbness in an arm or leg

pain in the arms, neck, back, or jaw

dizziness

faintness If a doctor prescribes male testosterone injections to an adolescent to treat a constitutional delay of growth and puberty, the goal will be to achieve an accelerated growth spurt during puberty. This therapy should not affect the final adult height that the adolescent reaches. Side effects People may experience some mild side effects from testosterone injections, such as: breast enlargement or pain

acne

a deeper voice

tiredness

hoarseness

back pain

redness, bruising, pain, bleeding, or hardness at the injection site

trouble sleeping or staying awake

weight gain

joint pain

mood swings

headaches A person should speak to their doctor if they experience more serious side effects, such as: nausea or vomiting

lower leg pain, redness, or warmth

swelling of the hands, ankles, feet, or lower legs

trouble breathing

yellowing of the eyes or skin

excessively long lasting erections

changes in urination, such as difficulty urinating, increased frequency, weak flow, urinary urgency, or blood in the urine

severe pain in the upper right part of the abdomen

mood changes, including depression, anxiety, or feeling suicidal

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