Tropical Weight Loss
Photo: Andres Ayrton
Researchers found that in people who lost more than 5% of body weight in the first year, those taking metformin had greater success with maintaining weight loss in years 6 to 15. However, taking the drug without following other healthy habits may not lead to weight loss.
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Read More »Doctors typically prescribe metformin for people with diabetes or prediabetes to help manage the condition. People who take the medication may experience weight loss. Recall of metformin extended release In May 2020, the Food and Drug Administration (FDA) recommended that some makers of metformin extended release remove some of their tablets from the U.S. market. This is because an unacceptable level of a probable carcinogen (cancer-causing agent) was found in some extended-release metformin tablets. If you currently take this drug, call your healthcare professional. They’ll advise whether you should continue to take your medication or if you need a new prescription. Metformin is a drug for managing blood sugar levels in people with type 2 diabetes. You may have heard that metformin can also help you lose weight. But is it true? Here’s what you should know about what metformin can do for weight loss, as well as why a doctor or healthcare professional may prescribe it for you. Can metformin cause weight loss? The FDA doesn’t approve metformin as a stand-alone weight loss drug. However, people using metformin for other means may lose weight as a side effect. The exact mechanism of this is unclear. Unlike other diabetes medications, metformin doesn’t cause weight gain. Appetite reduction One theory is that metformin prompts you to eat less by reducing your appetite. However, the methods by which metformin affects appetite aren’t clear. Metformin may interfere with the gut microbiota, prompt the release of appetite-suppressing hormones, and affect appetite-regulating parts of the brain. Some people who take metformin may also experience diarrhea, bloating, and nausea. These side effects may reduce how much a person wishes to eat. Long-term weight loss One long-term study of people with diabetes assessed weight loss over 15 years. Researchers found that in people who lost more than 5% of body weight in the first year, those taking metformin had greater success with maintaining weight loss in years 6 to 15. However, taking the drug without following other healthy habits may not lead to weight loss. Individuals who follow a healthy diet and exercise while taking metformin tend to lose the most weight. In addition, any weight loss you have may only last as long as you take the medication. That means if you stop taking metformin, there’s a good chance you’ll return to your original weight. And even while taking the drug, you may slowly gain back any weight you’ve lost. Will my doctor prescribe metformin for weight loss? If you have type 2 diabetes or prediabetes and are overweight or have obesity, a doctor may prescribe metformin to help you manage your diabetes or lower your risk of developing it. In fact, a doctor might prescribe metformin for weight loss even if you don’t have diabetes or prediabetes. This is an off-label use. Off label means that the FDA hasn’t approved a drug for a specific use, which in this instance is as a weight loss aid. As a result, there’s less information about how effective it is for this purpose.
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Read More »What is the dose for weight loss? Metformin is a diabetes medication. There are no official dose recommendations for it as a weight loss aid. If a doctor prescribes metformin for you off label, they’ll decide on a dose that’s right for you and your medical circumstances. You’ll likely start metformin at a low dose and gradually increase it over a few weeks. This can help minimize any side effects. One off-label use of metformin is for antipsychotic drug-induced weight loss. Doses for immediate-release metformin can range from 750 mg to 2,000 mg . Extended-release doses may range from 500 mg to 2,000 mg. What if I’m worried about my weight loss? Keep in mind that metformin is a relatively safe drug with side effects that usually go away over time. Any weight loss you may have while taking it should be gradual and minimal and not cause alarm. If you’re concerned about the amount of weight you’ve lost while taking metformin, talk with a doctor. They can help determine what’s causing your weight loss. Whether or not you take metformin, you should call a doctor if you’re losing weight rapidly and have no energy or appetite. In general, you should feel free to call any time you have questions or concerns about your health or your weight. Learn why you may experience unexplained weight loss here.
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