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How many kg can you lose on Ozempic?

How much weight did people lose weight with Ozempic®? Based on the STEP-1 study, people on Semaglutide lost 15.3 kg compared to the placebo group who only lost 2.6 kg. This was at the end of 68 weeks.

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With every new medication released for weight loss, people want that new medication. When Saxenda® was released people were keen to try this new injection and has been popularly called the “skinny jab”. Saxenda® belongs to he class of medications called GLP-1 Now another Glucagon Like Peptide (GLP-1) called Ozempic® has been approved for weight loss in people with type 2 diabetes. The same medication Ozempic®, that is Semaglutide is now licensed by FDA for chronic weight management and the trade name is Wegovy®.

How much weight did people lose weight with Ozempic®?

Since the release of the research studies, thousands of people are enquiring about the new medication. Research studies have been published in the

The Lancet:

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00213-0/fulltext

and

in the New England Journal of Medicine:

https://www.nejm.org/doi/full/10.1056/NEJMoa2032183

Based on the STEP-1 study, people on Semaglutide lost 15.3 kg compared to the placebo group who only lost 2.6 kg. This was at the end of 68 weeks. The dose used was Semaglutide 2.4mg weekly. The STEP-2 study showed that people on Semaglutide lost about 10% of their body weight. The STEP-2 study was done in people with type 2diabetes and the dose used was Semaglutide 2.4mg weekly. People need to understand the outcome was due to the fact that people were supported by the research team with life style changes and they were motivated and they engaged regularly. Just taking this injection and not adapting new life style changes will not result in similar weight loss.

Real world data on Semaglutide

The above weight loss was in the research studies. Weight loss in people after the medication is released, that is post marketing is also analysed and is Called the real world data. This provides a true picture of the effectiveness of the medication in real life as research data are highly biased. The weight loss in people in the real world, especially those with type 2 diabetes was significant.

https://www.healio.com/news/endocrinology/20210211/weekly-semagltide-injection-associated-with-substantial-weight-loss-in-obesity

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Can I get Ozempic in the UK?

Ozempic is available on the NHS, but it is only licensed to be used in patients with type 2 diabetes mellitus. Because of this, the NHS do not offer it as a treatment to those that need help with weight loss.

Ozempic and Wegovy are both brand names for Semaglutide injections.

It’s manufactured by Novo Nordisk, which is the company that invented the medication. For several years, Ozempic was the only form of Semaglutide that was available. However, in 2020, Novo Nordisk launched Rybelsus – a tablet version of Semaglutide that’s taken daily. Now, patients can request their preferred treatment for consideration during a consultation with a qualified prescriber, whether they’d like to take a weekly injection or a daily tablet. Ozempic is still the most common form of Semaglutide used as a diabetes treatment, as most people that currently take it have been used to using the injections. Ozempic is the version of Semaglutide that is officially approved and licensed for the treatment of Type 2 diabetes and it can only be used for this purpose. However, the FDA in the USA have approved Semaglutide for chronic weight management and the UK is swiftly following them, licensing this treatment under the name Wegovy. The maximum strength of Ozempic available is the 1.0mg pen as this is the dose that gives optimal results in controlling people’s Type 2 diabetes. However, Wegovy will be released with a therapeutic dose of 2.4mg for the purposes of weight management, meaning that the dose of Semaglutide is higher in Wegovy than it is in Ozempic. The difference, therefore between the two medications is their licenses – Ozempic is licensed to treat type 2 diabetes mellitus, whereas Wegovy is licensed for weight management, despite both containing the same active drug. A few weight loss and diabetes medications follow the same licensing and naming conditions. Here’s an example of some of the most popular treatments that have different names when used for diabetes and weight management.

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