Tropical Weight Loss
Tropical Weight Loss
Photo: Max Vakhtbovych
Metformin improves menstrual cycle regularity and lowers body mass index (BMI), testosterone, and luteinizing hormone (LH) within 6 months of treatment in women with polycystic ovary syndrome (PCOS) who are normal weight or overweight, new results show.
Stephens recommends using the juice from two to three lemons (about four to six tablespoons) throughout the day, and drinking one or two glasses of...
Read More »
“In general, it can take anywhere from weeks to months—even years,” says Dr. Chen. If after one to two years skin is still loose, it may not get...
Read More »Metformin improves menstrual cycle regularity and lowers body mass index (BMI), testosterone, and luteinizing hormone (LH) within 6 months of treatment in women with polycystic ovary syndrome (PCOS) who are normal weight or overweight, new results show. The study is one of the few to examine the long-term effects of metformin, which was given daily for 2 years, although researchers found that most benefits emerged after 6 months, with over 40% of patients achieving normal menstruation by this point. The trial is also the first to evaluate metformin in all subgroups of women with PCOS, as most prior studies have looked at patients who are obese and/or hyperandrogenic (androgen excess), say the authors led by Po-Kai Yang, MD, from the National Taiwan University Hospital, Taipei City. The study was published online January 9 in the Journal of Clinical Endocrinology & Metabolism. They found that there are differences in treatment response to metformin between different BMI/testosterone subgroups — of which there were four — which could help in patient selection for treatment. For menstrual regularity — the primary endpoint — the normal weight, excess testosterone subgroup had the most significant sevenfold improvement from baseline, whereas the overweight, normal testosterone subgroup had the longest duration of improvement and the highest rate of normal menses after treatment (achieved by > 60% vs baseline). The reason for the difference in menstrual response between BMI/testosterone phenotypes is unknown, "but probably relates to the different pathophysiological mechanisms displayed over the spectrum of clinical manifestations in PCOS," the researchers say.
The 5:2 diet involves eating as you normally do 5 days of the week and restricting your calorie intake to 500–600 on the remaining 2 days. Eat Stop...
Read More »
Water can be really helpful for weight loss. It is 100% calorie-free, helps you burn more calories and may even suppress your appetite if consumed...
Read More »With regard to BMI, lean women with PCOS often have elevated LH, while obese women with PCOS have a greater tendency for insulin resistance. Testosterone is thought to be a determinant of menstrual regularity. Metformin is an insulin sensitizer, and in women with PCOS it has been shown to have beneficial effects on hyperinsulinemia, hyperandrogenemia, ovarian steroidogenesis, menstrual cycles, blood pressure, and pregnancy rates, the authors note. They compared the response, including the proportion of patients with regular menstruation during treatment (the primary outcome), as well as hormonal, metabolic, and anthropometric profiles, in 119 overweight and normal weight women with PCOS (Rotterdam criteria) treated with daily metformin over 2 years Daily Metformin for 2 Years, But Most Benefit Seen in First 6 Months Patients started on 500 mg/day of metformin in the first month, followed by 1000 mg/day in the second month, and 1500 mg/day from the third to 24th month. (A decrease to 1000 mg/day was allowed in those with intolerable gastrointestinal side effects.) The efficacy of menstrual cycle restoration was then assessed according to baseline BMI and testosterone status. Patients were stratified into four subgroups: normal weight, normal testosterone (n = 49); normal weight, elevated testosterone (n = 23); overweight, normal testosterone (n = 27); and overweight, elevated testosterone (n = 20). At baseline, the proportions of patients with hyperandrogenism/anovulation, hyperandrogenism/polycystic ovarian morphology, anovulation/polycystic ovarian morphology, and all three were 17.6%, 12.6%, 20.2%, and 49.6%, respectively. Overall, 47 patients were overweight, and 72 were normal weight. The proportion of patients with normal menstrual cycles was higher in the overweight than normal weight subgroup. At 6 months, the proportion of women with normal menses was 47% of normal weight, normal testosterone patients; 43% of normal weight, elevated testosterone patients; 42% of overweight, normal testosterone patients; and 42% of overweight, elevated testosterone patients. Those categorized as normal weight, elevated testosterone (who had the lowest rate of normal menses at study entry) showed the most improvement by 6 months (odds ratio 7.21, normal menses vs baseline).
Six weight-loss drugs have been approved by the U.S. Food and Drug Administration (FDA) for long-term use: Bupropion-naltrexone (Contrave)...
Read More »
What Not to Eat for Weight Loss? Bakery Products. Foods that are made using maida, also known as white flour or refined flour are high in calorie...
Read More »Those categorized as overweight, normal testosterone at baseline showed continued improvement to 12 months and had the highest proportion of patients with normal menstrual cycles (63%) after 2 years of treatment.
Here are 5 side effects of drinking too much lemon water: It can cause enamel erosion or tooth decay. Lemons are highly acidic citrus fruits. ......
Read More »
Rupture – we are regularly asked whether the balloon can burst and although we have to make you aware that this is a possibility, the risk is very...
Read More »
Savory Late-Night Snacks Popcorn. When winding down before bed with a bag of popcorn and a show, you may wonder, is popcorn a good late-night...
Read More »
14 BEST FOODS TO PREVENT HAIR FALL #1 - Eggs. Eggs are a great source of protein and biotin, both of which promote hair strength. ... #2 - Carrots....
Read More »
Promotion
Promotion
Promotion