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How does testosterone cause fat loss?

Testosterone helps maintain muscle mass, increase the number of calories you burn and may keep you motivated to stay physically active — all of which are associated with a lower risk of weight gain and obesity.

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The term “testosterone supplement” can refer to three things: illicit anabolic steroids, testosterone replacement therapy and testosterone boosters.

Illicit Anabolic Steroids

Synthetic steroids related to testosterone are collectively known as anabolic steroids. The term may also refer to testosterone itself. Some bodybuilders misuse anabolic steroids to increase testosterone beyond normal levels and boost muscle growth. Yet abusing anabolic steroids is illegal in many countries, including the US ( 14 ). Healthy men with normal testosterone levels should not take anabolic steroids in any form, since long-term misuse can cause adverse side effects. These include sexual dysfunction, aggressive behavior, liver problems and heart disease ( 15 , 16 , 17 ). Some researchers have pointed out that not all of these side effects apply to testosterone itself but rather to its synthetic derivatives. In fact, testosterone plays a valid role in the treatment of some medical conditions ( 18 ). For instance, it is legally prescribed to normalize testosterone levels in deficient men, a treatment known as testosterone replacement therapy ( 19 ). While valid testosterone replacement therapy may promote weight loss in obese men, anabolic steroid misuse is not a recommended weight loss strategy. Excessive muscle mass may be difficult to maintain in the long term and unused muscles tend to turn into fat over time. Summary: Some bodybuilders misuse testosterone or related synthetic forms. Long-term misuse may lead to serious health problems.

Testosterone Replacement Therapy

This hormone is often legally prescribed to treat testosterone deficiency (hypogonadism) or other medical conditions. The treatment is known as testosterone replacement therapy and is performed under medical supervision. It can be administered as a supplement, skin patch, cream or injection. There is some evidence that replacement therapy can lead to weight loss in obese patients with testosterone deficiency ( 20 , 21 , 22 , 23 ). One 56-week study in 100 obese men on a reduced-calorie diet found that injections improved weight loss by 6.4 pounds (2.9 kg) compared to those who didn’t receive any treatment. While both groups lost muscle mass as well as fat mass on a low-calorie diet, testosterone caused significant muscle regain during the weight maintenance period ( 24 ). It leads to weight loss by promoting muscle growth, which in turn increases the number of calories burned. It may also reduce fatigue, enhance motivation and promote greater physical activity. All of these factors play a major role in weight loss ( 8 , 25 ). Keep in mind that these studies examined the effects of replacement therapy in deficient men under medical supervision. There is no evidence that replacement therapy causes weight loss in healthy men with normal testosterone levels.

Summary: Testosterone replacement therapy promotes weight loss in obese, testosterone-deficient men.

Testosterone Boosters

Also known as “natural testosterone supplements,” testosterone boosters increase the natural production of this hormone within your body.

These supplements do not contain any testosterone and are usually plant-based.

Some boosters, such as ashwagandha, D-aspartic acid and fenugreek seed extract, may raise testosterone levels and improve muscle growth in men who have low levels, although the evidence is inconsistent ( 26 , 27 , 28 ). However, many of the health claims associated with boosters are not supported by science. For instance, Tribulus terrestris, a supplement commonly sold as a booster, does not appear to raise levels ( 29 ). Currently, no studies have shown significant weight loss with testosterone boosters, although some tend to reduce fat mass. Summary: Testosterone boosters enhance the natural production of testosterone within the body. Studies suggest that certain boosters may benefit men who are deficient.

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What is the main cause of low testosterone?

Causes of Low Testosterone Medicine side effects, such as from chemotherapy. Testicle injury or cancer. Problems with glands in the brain (hypothalamus and pituitary) that control hormone production. Low thyroid function.

Your provider will likely have you get a blood test to check your testosterone level. You will also be checked for other causes of your symptoms. These include medicine side effects, thyroid problems, or depression. If you have low testosterone, hormone therapy may help. The medicine used is man-made testosterone. This treatment is called testosterone replacement therapy, or TRT. TRT can be given as a pill, gel, patch, injection, or implant. TRT may relieve or improve symptoms in some men. It may help keep bones and muscles strong. TRT seems to be more effective in young men with very low testosterone levels. TRT can also be helpful for older men.

TRT has risks. These may include:

Infertility

Enlarged prostate leading to difficulty urinating

Blood clots

Worsening heart failure

Sleep problems

Cholesterol problems

At this time, it is unclear whether TRT increases the risk of heart attack, stroke, or prostate cancer. Talk with your provider about whether TRT is right for you. If you do not notice any change in symptoms after treatment for 3 months, it is less likely that TRT treatment will benefit you. If you decide to start TRT, be sure to see your provider for regular checkups.

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