How do you qualify for Mounjaro?

Mounjaro is intended for adults with a body mass index greater than 30, or greater than 27 with an obesity-related medical condition (i.e. diabetes, high blood pressure, high cholesterol, sleep apnea).

trueyouweightloss.com - Mounjaro - True You Weight Loss

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WHAT IS MOUNJARO? HOW DOES IT WORK?

Mounjaro builds on the work of semaglutide, which is a medication that boosts levels of glucagon-like-peptide (GLP-1) in the body. Like semaglutide, it targets the GLP-1 receptor to boost GLP levels. But it also targets a second receptor, GIP (glucose dependent insulinotropic polypeptide). GIP is another hormone released into the digestive tract after we eat, and it appears to regulate weight through receptors in the brain and fat cells. More importantly, GLP-1 and GIP are synergistic and enhance each other’s effects. By combining the action of both hormone receptors, Mounjaro leads to more weight loss overall. Mounjaro comes in single-use, pre-filled pens. Each pen is 1 dose. To use the pen, simply remove the cap, turn to unlock the pen, and press the pen firmly against the skin. Press the pen button until a click is heard. The medication will be delivered subcutaneously. A second click will be heard when the medication is fully delivered. Most patients inject the medication in the upper arm, belly, or thigh.

HOW OFTEN DO I TAKE THE MEDICATION?

Once per week. Choose a day that is convenient for you, and set a reminder so that you don’t forget! The starting dose is 2.5 mg, which is taken once weekly for a month. The dose can then be increased to 5 mg, also taken for a month. The dose can be further increased by 2.5 mg every month, up to a maximum dose of 15 mg. This process can take up to 20 weeks.

HOW LONG DO I STAY ON THE MEDICATION?

Mounjaro is considered a long-term medication. If you are tolerating it well, and it is helping you to lose weight, it is recommended to continue the medication.

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Which diabetic drug causes the most weight loss?

Currently, one of the best glucose-lowering medications for weight management is Wegovy (semaglutide), which resulted in a 14.9% reduction in body weight – significantly lower than tirzepatide's 22.5% reduction.

diatribe.org - FDA Accelerates Review of Type 2 Drug Mounjaro for Weight Loss

Mounjaro, a drug approved in 2022 to treat type 2 diabetes, has also shown remarkable weight-loss effects, reducing trial participants’ weight by over 20%. Regulators have taken notice, granting the medication a fast-track designation for its review for the treatment of obesity. The US Food and Drug Administration (FDA) approved tirzepatide for the treatment of type 2 diabetes in May, when Eli Lilly & Co. began marketing the medication as Mounjaro. While the drug is currently approved as a glucose-lowering therapy for type 2 diabetes, participants in the SURMOUNT-1 clinical trial on a 15mg dose of tirzepatide experienced an astonishing 22.5% reduction in body weight. Lilly announced on Oct. 6 that the FDA granted tirzepatide a “fast track” review to be designated as a treatment for obesity. To receive this label, Lilly will be using data from the SURMOUNT-1 trial and the ongoing SURMOUNT-2 trial, which is investigating tirzepatide in people with type 2 diabetes who have excess weight or obesity. Although the SURMOUNT-2 trial will not be completed until April 2023, the FDA’s fast-track designation allows for rolling submission of trial data. This means the FDA can review data as it comes in, instead of waiting for the entire trial to conclude first. This expedites the review process, resulting in a potentially sooner approval date. The FDA grants these fast-track designations to medications that could fill a serious unmet medical need. With the rising rates of adult and childhood obesity, coupled with the limited options for medical treatment, tirzepatide could be a game-changer in the obesity epidemic. Currently, one of the best glucose-lowering medications for weight management is Wegovy (semaglutide), which resulted in a 14.9% reduction in body weight – significantly lower than tirzepatide’s 22.5% reduction.

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