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Does weight loss indicate heart problems?

Weight loss can occur as a result of heart failure. However, it is not likely that healthy people who experience weight loss or achieve a moderate body weight will develop any significant cardiovascular issues. Cardiac cachexia is a serious condition that occurs alongside heart failure.

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Weight loss and heart failure share a connection. People living with heart failure may experience unexpected and extreme weight loss. When weight loss occurs with heart failure, it is known as cardiac cachexia. This condition is associated with an increased mortality rate among people living with heart failure. The following article reviews how heart failure and weight loss relate to each other, with a focus on cardiac cachexia. Does weight loss cause heart disease? In one 2019 observational study , researchers noted increased cases of premature death, including from heart disease, in people who had lost weight after experiencing obesity after the age of 47. The study authors recommend that younger individuals take steps to prevent weight gain throughout their life. In another study , researchers noted an increased mortality rate in people living with congestive heart failure who experienced weight loss compared with those who did not lose weight. They noted that the risk was highest in people with obesity. However, it is important to remember that weight loss can be unintentional. For example, people with cancer may experience weight loss and mortality due to the condition. Weight loss can still be healthy Losing excess weight can be an effective way to reduce a person’s risk of several potentially life threatening conditions. These include: heart disease

hypertension

type 2 diabetes Research is more extensive in these benefits than the possible cardiac risks of sudden weight loss in some groups. Findings from one observational study may not be representative of potential results from a randomized group. The benefits of losing excess weight may far outweigh the possible cardiac risks associated with a sudden drop in weight. Can heart failure cause weight loss? People living with heart failure can develop rapid weight loss. This is known as cardiac cachexia, and the outlook for people with the condition is not positive due to an increased risk of mortality. Cardiac cachexia is a condition that causes a person to lose weight, skeletal mass, and muscle mass. It can also cause inflammation and affect several organs. The condition can cause a person to have an increased risk of death regardless of other risk factors associated with heart disease. Causes of cardiac cachexia The exact cause of cardiac cachexia is not clear. Researchers do know it is multifaceted. They also know that several underlying factors may contribute to its development, including: food intake

an imbalance between anabolic and catabolic processes

gastrointestinal abnormalities

neurohormonal activation

immunological activation

poor cardiac output

nutrient malabsorption

Outlook of cardiac cachexia Cardiac cachexia is associated with an increased risk of premature death, independent of other risk factors, such as age or overall health. A person living with cardiac cachexia will therefore have an increased risk of death even if they have no other risk factors that would indicate a shortened lifespan. A person living with heart failure or heart disease should speak with a doctor if they experience unexplained weight loss. This could be a sign they have developed cardiac cachexia. A doctor will likely ask the person questions about their symptoms and determine how much weight they have lost. Though diagnosis criteria can vary, many doctors diagnose cardiac cachexia after noting more than 5% weight loss over 12 months or a BMI of less than 20. In addition, a person will have experienced at least three of the following: anorexia

fatigue

decrease in muscle strength

anemia

increase in inflammatory markers

low blood albumin levels

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Which part of the body dies last?

The brain and nerve cells require a constant supply of oxygen and will die within a few minutes, once you stop breathing. The next to go will be the heart, followed by the liver, then the kidneys and pancreas, which can last for about an hour. Skin, tendons, heart valves and corneas will still be alive after a day.

Asked by: Andy Hurman, Bedford

Definitely not. The brain and nerve cells require a constant supply of oxygen and will die within a few minutes, once you stop breathing. The next to go will be the heart, followed by the liver, then the kidneys and pancreas, which can last for about an hour. Skin, tendons, heart valves and corneas will still be alive after a day. White blood cells, which are more independent, can keep going for almost three days. Subscribe to BBC Focus magazine for fascinating new Q&As every month and follow @sciencefocusQA on Twitter for your daily dose of fun science facts.

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