Does phentermine ruin your metabolism?

While phentermine is an effective weight loss drug and works by suppressing appetite, it does not influence the body's metabolism and genetics—which are responsible for more than 80% of body weight.

novi-health.com - Here's Why Using Phentermine for Weight Loss Isn't the Best Idea

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Phentermine is one of the oldest FDA-approved medications for weight loss, gaining recognition in 1959. The initial products combined phentermine with fenfluramine and dexfenfluramine. Unfortunately, researchers found these to cause cardiac complications such as valvular abnormalities in users. As a result, the FDA removed fenfluramine and dexfenfluramine from the market in late 1997. Phentermine alone or in combination with topiramate is relatively safer. That is why the FDA re-approved the medication for short-term (3-month) weight loss use in 2012.

Apidex: 15.0 to 37.5 mg/day once or twice daily formulation

Lomaira: An 8 mg, 3 times a day package

Qsymia: A phentermine/topiramte combination available in varying strengths; 3.75 mg/23 mg, 7.5 mg/46 mg, 11.25 mg/ 69 mg, 15 mg/92 mg

How does phentermine work?

Phentermine is structurally similar to amphetamines. Thus, it lowers appetite through its indirect sympathetic action. In other words, phentermine triggers the release of noradrenaline, the 'fight or flight’ hormone that enables the body to react in emergencies. It achieves this by directing blood flow to essential organs such as the heart and brain. As a result, blood flows away from the gastrointestinal tract, suppressing appetite and promoting a feeling of fullness. In addition, phentermine directly inhibits neuropeptide Y—the main hunger signaling pathway in the brain. This also reduces cravings and hunger. Topiramate is an anticonvulsant often added to phentermine to boost weight loss. How it achieves this isn't precisely known, but studies attribute the effect to its appetite suppressive qualities.

Who is phentermine suitable for?

In general, anyone who has attempted to lose weight and could not achieve their target weight is a candidate for weight-loss drugs such as phentermine. More specifically, the FDA recommends phentermine for individuals with a BMI of more than:

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What is the success rate of phentermine?

Phentermine has an average rating of 8.7 out of 10 from a total of 2014 ratings for the treatment of Weight Loss (Overweight). 84% of reviewers reported a positive experience, while 5% reported a negative experience.

drugs.com - Phentermine User Reviews for Weight Loss (Overweight) - Drugs.com

User Reviews for Phentermine

Phentermine has an average rating of 8.7 out of 10 from a total of 2,934 ratings on Drugs.com. 84% of reviewers reported a positive experience, while 5% reported a negative experience. Condition Avg. Rating Reviews Compare Weight Loss (Obesity/Overweight) 8.7 2934 reviews 66 medications Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Phentermine

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Frequently asked questions

This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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