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Does L-carnitine affect hair?

Studies have shown that L-carnitine stimulates human hair growth; via its ability to increase proliferation and decrease apoptosis in follicular cells. Carnitine literally increases the energy supply to the hair follicle matrix, which is necessary for the full functioning of potassium channels in hair follicles.

custommedicine.com.au - Natural Hair Loss Treatment
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Natural Hair Loss Treatment

Potassium ion channels exist within the dermal papilla cells of human hair follicles and have been the target for hair loss treatments with such medications such as Minoxidil, a potassium channel agonist. Potassium ion channels have been implicated in a vast array of diseases ranging from Androgenetic Alopecia to Diabetes. These small pore-forming protein structures control the transport of potassium ions across the hair follicle’s cell membranes and are essential for maintaining the follicle’s full biological activity and function. It has been conclusively shown that in Androgenetic Alopecia the function of potassium channels within hair follicles progressively degrade. The result is reduced membrane potential and impaired ion transfer across the follicle’s cellular membranes –culminating over time in atrophying follicles and loss of hair. A research team led by Dr Thomas Whitfield PhD, formulated, tested and patented an oral complex of nutrients that essentially have the same effect on potassium channels and hair growth as oral minoxidil without side effects, and significant cross over anti-aging health benefits. This complex of nutrients simply consist of a combination of Potassium chloride, Carnitine tartrate, Branched Chain Amino Acids, Niacin, and Biotin. According to the research, this particular combination of nutrients has the effect of:

• Boosting energy levels in the hair follicles

• Maintaining The Cell Membrane Potential of Hair Follicles*

• Stimulating de novo Synthesis of Potassium Channels in Hair Follicles

• Stimulating Potassium Channel Activity & Functionality

Studies have shown that L-carnitine stimulates human hair growth; via its ability to increase proliferation and decrease apoptosis in follicular cells. Carnitine literally increases the energy supply to the hair follicle matrix, which is necessary for the full functioning of potassium channels in hair follicles. According to the research this combination stimulates the synthesis of cardiolipin, a key component of the plasma membrane of dermal papilla cells in hair follicles. Cardiolipin plays a crucial role in maintaining the potential and integrity of hair follicle cell membranes. In short it provides the ideal lipid environment for potassium channels to flourish and function at peak efficiency.” The specific potassium channel found in human hair follicles is comprised of the Branched Chain Amino Acids, L-Leucine, Isoleucine and Valine. L-carnitine helps maintain cellular energy metabolism by assisting in the transport of fat through the cell membrane and into the mitochondria within the cell, where fats are oxidized to produce the cellular energy ATP. This enhances potassium channel function and facilitates ion transport across the cellular membranes. Niacin is structurally related to minoxidil and both maintains potassium channel function, which like oral minoxidil, stimulates hair growth. In addition we also incorporate Vitamin D and Zinc which are also essential for hair growth. Our lab produces a combination which contains the following as a daily dose:

Potassium Chloride 191 mg.

L-Carnitine-L-Tartrate 800 mg.

L-Leucine 150mg.

Isoleucine 75 mg.

Valine 75 mg.

Niacin 50mg.

Biotin 1mg.

Zinc 20mg (as picolinate).

Vitamin D 1000iu

This combination is available online from our lab. To order you must register for an online consultation which is free or alternatively contact us.

REFERENCES

L-Carnitine–L-tartrate promotes human hair growth in vitro

Experimental Dermatology

Volume 16, Issue 11, pages 936–945, November 2007

Kerstin Foitzik1,2, Edo Hoting3, Thomas Förster4, Paolo Pertile5, Ralf Paus2

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How can I plump up my face after weight loss?

For sagging around the jawline or cheeks, where weight loss changes can be most prevalent, you may want to consider injectables, says Desai. “We can use fillers, such as hyaluronic acid-based fillers, and inject them into these areas of volume depletion to plump them up, which also lifts the skin.”

Most weight-loss milestones are celebrated. More energy! Lower blood pressure! Looser jeans! But there’s one we tend to get quiet—if not silent—about: changes to the skin. More pointedly, looser skin and wrinkles.

After all the effort that’s put into eating healthier, walking more, and prioritizing your wellness, it can be deflating to see this unexpected change in the mirror, as if you’ve pressed fast-forward on the aging process. You may even feel younger, so what’s up with those jowls—and why didn’t anyone give you a head’s up about this?

“Most patients are happy about the weight loss, but often feel discouraged when they see their skin changes,” says Marisa Garshick, M.D., a dermatologist in New York City. Of course, you can (and should) feel all your feelings, whether that’s disappointment at newfound winkles or pride in the lines that now grace your face. But whichever side you land on, here’s one thing we can all agree on: It’s time to start talking about how weight loss affects our facial skin. Just like plateaus and non-scale victories, complexion changes are a real and natural part of the weight-loss experience. And normalizing (and celebrating!) this shift can only better prepare you for the journey. So let’s take a science-backed look at the causes and explore what you can do about them if (big if!) that’s the route you choose to go.

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