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Premenopausal women with higher coffee intake had a higher percentage of breast density. Postmenopausal women on hormone therapy who had higher coffee and caffeine intake had a lower percentage of breast density.
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Read More »The short answer is yes. Caffeine can affect breast tissue. However, caffeine doesn’t cause breast cancer. The details are complex and can be confusing. The bottom line is that the connection between caffeine and breast tissue shouldn’t necessarily change your coffee or tea drinking habits. Here’s what we know, in brief: Caffeine isn’t a risk factor for breast cancer. There may be a small association between breast tissue density and caffeine. This doesn’t mean a cause. Many studies have concluded that dense breast tissue is a strong risk factor for breast cancer. In this article, we’ll delve deeper into caffeine, breast density, and the connection between breast density and breast cancer. Caffeine and dense breast tissue There are very few studies of caffeine and breast tissue density, and results are mixed. A 2000 study found no association of caffeine to breast density. Similarly, a 2019 study of adolescents who consumed caffeine found no association with breast density in premenopausal women. However, a 2018 study of 4,130 healthy women found a small association between caffeine intake and breast density. The study results differed, depending on whether the women were premenopausal or postmenopausal: Postmenopausal women with a higher caffeine or decaffeinated coffee intake had a lower percentage of breast tissue density. Premenopausal women with higher coffee intake had a higher percentage of breast density. Postmenopausal women on hormone therapy who had higher coffee and caffeine intake had a lower percentage of breast density. Because hormone therapy tends to be associated with increased breast density in general, the study suggests that caffeine intake might reduce this effect. What’s in caffeine that might affect breast tissue? The connection between caffeine and breast tissue density isn’t fully understood. It’s suggested that the many biologically active compounds (phytochemicals) in caffeine may stimulate enzymes involved with estrogen metabolism and decreasing inflammation. These phytochemicals may also inhibit gene transcription by adding methyl groups to the DNA molecules. In animal tests, coffee compounds suppressed the formation of breast tumors, as reported in a 2012 study of caffeine and breast cancer . A 2015 study found that caffeine and caffeic acid had anticancer properties in relation to estrogen receptor genes. Breast screening risk vs. benefit Whether to have yearly supplemental breast screening if you have dense breasts is an individual decision. Discuss the pros and cons with a doctor. Supplemental screening increases the early detection of breast cancer in dense breasts. And catching a breast cancer tumor early has a better outcome. The U.S. Preventive Services Task Force advised in 2016 that the current evidence wasn’t sufficient “to assess the balance of benefits and harms” of additional screening for women with dense breasts. Potential harms include: possible false positives
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