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Although rare, it's possible for Wegovy to cause depression or increase your risk of suicidal thoughts. If you already have depression or a mood condition, taking Wegovy may make your condition worse. In this case, your doctor may recommend monitoring your mood more often while you're taking Wegovy.

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Overview Wegovy (semaglutide) is a brand-name prescription medication. The Food and Drug Administration (FDA) has approved it for long-term weight loss in certain adults. This medication should be used along with a low calorie diet and exercise to help manage your body weight. Here are some fast facts about Wegovy: Active ingredient: semaglutide

semaglutide Drug class: glucagon-like peptide-1 receptor agonist

glucagon-like peptide-1 receptor agonist Drug form: solution for subcutaneous injection

solution for subcutaneous injection FDA approval year: 2017 If Wegovy works for you, your doctor will likely recommend that you take it long term. As with other drugs, Wegovy injections (shots) can cause side effects. Read on to learn about potential common, mild, and serious side effects. For a general overview of Wegovy, including details about its uses, see this article. More common side effects of Wegovy Wegovy can cause certain side effects, some of which are more common than others. These side effects may be temporary, lasting a few days to weeks. However, if the side effects won’t go away, bother you, or become severe, be sure to talk with your doctor or pharmacist. These are just a few of the more common side effects reported by people who took Wegovy in clinical trials: abdominal pain

nausea*

diarrhea*

vomiting

constipation* * For more information about this side effect, see “Side effect specifics” below. FAQs about the side effects of Wegovy Wegovy may cause several side effects. Here are some frequently asked questions about the drug’s side effects and their answers. Are there reviews from people who experienced side effects with Wegovy injections? If you’d like to learn more about what to expect from taking Wegovy, the best thing to do is to talk with your doctor. You may also be able to find testimonials online about side effects that people taking Wegovy reported. However, it’s important to note that each person taking Wegovy may have their own experience with the drug since each person can respond to a medication differently. So online reviews of Wegovy written by other people may not be reliable sources for how your body will react to the drug. If you have questions about side effects that you may experience with Wegovy, talk with your doctor or pharmacist. Are there long-term side effects of Wegovy? Although uncommon, it’s possible to experience long-term side effects from taking Wegovy. Examples of long-term side effects that may occur with this drug include: gallbladder problems

kidney problems

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diabetic eye problems

depression or suicidal thoughts or behaviors

gastroesophageal reflux disease (GERD) If you are concerned about long-term side effects that may occur from taking Wegovy, talk with your doctor or pharmacist. They may also be able to recommend ways to limit these side effects occurring. Precautions for Wegovy Before starting Wegovy, be sure to tell your doctor about any medical conditions that you have. Boxed warning: Risk of thyroid cancer This drug has a boxed warning for a risk of thyroid cancer. This is a serious warning from the Food and Drug Administration (FDA). For details, see the “Side effect specifics” section above. Other precautions Be sure to talk with your doctor about your health history before you take Wegovy. This drug may not be the right treatment option for you if you have certain medical conditions or other factors that affect your health. These are considered drug-condition or drug-factor interactions. The conditions and factors to consider include: Pancreas problems. Tell your doctor if you have any pancreas conditions, such as pancreatitis, before starting Wegovy. Although rare, it’s possible for Wegovy to cause pancreas problems to occur. And if you already have a pancreas condition, taking this medication can make your condition worse. If you have a pancreas condition, your doctor can help determine whether Wegovy may be safe for you. Kidney problems. If you have any kidney problems, tell your doctor before taking Wegovy. This medication can cause kidney problems to occur and may make existing kidney problems worse. In this case, your doctor can help determine whether Wegovy may be safe for you. Allergic reaction. If you’ve had an allergic reaction to Wegovy or any of its ingredients, your doctor will likely not prescribe Wegovy. Ask your doctor what other medications may be better options for you. Diabetes. Tell your doctor if you have diabetes before starting Wegovy. It’s possible for this medication to cause a low blood sugar level, and this risk may be higher if you have diabetes. So your doctor may recommend monitoring your blood sugar level more often if you have diabetes and are taking Wegovy. Diabetic eye problems. It’s possible for Wegovy to worsen diabetic retinopathy or a diabetic eye condition. So if you have this condition, taking Wegovy can make your symptoms worse. Due to this risk, your doctor may recommend monitoring your eyes more often while you’re taking Wegovy. Depression or mood problems. Although rare, it’s possible for Wegovy to cause depression or increase your risk of suicidal thoughts. If you already have depression or a mood condition, taking Wegovy may make your condition worse. In this case, your doctor may recommend monitoring your mood more often while you’re taking Wegovy. Wegovy side effects with alcohol There aren’t any known interactions between Wegovy and alcohol. However, it’s possible that drinking alcohol while taking Wegovy may increase your risk of side effects from the drug. For example, both Wegovy and alcohol can cause: nausea

vomiting

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headache

dizziness If you consume alcohol, talk with your doctor to find out whether it’s safe to do so while taking Wegovy. They can also advise how much is safe. Pregnancy and breastfeeding while taking Wegovy Wegovy may not be safe to take during pregnancy. It’s also not known whether it’s safe to take Wegovy while breastfeeding. There isn’t a benefit to losing weight during pregnancy, so your doctor likely won’t recommend taking this drug during pregnancy. They will likely recommend that you stop taking Wegovy at least 2 months before becoming pregnant. In addition, animal studies show that there may be risks to a developing fetus if it is exposed to Wegovy. For example, in animal studies, there was an increased risk of congenital anomalies (also known as birth defects) and pregnancy loss. However, animal studies don’t always indicate what may happen in humans. There is a pregnancy registry available for people who take Wegovy during pregnancy. A pregnancy registry is a collection of data that shows how a drug may affect a developing fetus. To join the pregnancy registry, call 800-727-6500 or talk with your doctor. In addition, it’s not known whether Wegovy passes into breast milk or what effects the drug may have on a child who is breastfed. In animal studies, the drug was present in breast milk. However, animal studies don’t always indicate what may happen in humans. If you’re pregnant or planning to become pregnant, talk with your doctor. You should also talk with them if you’re breastfeeding or considering it. Your doctor can help determine whether treatment with Wegovy is safe for you.

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