Tropical Weight Loss
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The possible link between phentermine and heart failure stems from rare reports of valvular heart disease in people who took the drug. The medication also may cause pulmonary hypertension, which can be fatal.
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Read More »A link may exist between phentermine and heart failure. There are rare reports of valvular heart disease in people who have taken this anti-obesity drug. Valvular heart disease involves damage to one or more of the valves in the heart. These valves open and close to regulate blood flow. Additionally, phentermine may cause another, equally serious, side effect: pulmonary hypertension. This is high blood pressure in the arteries of the lungs. People with cardiovascular disease or conditions affecting the heart and lungs should not take phentermine. This article discusses the association between phentermine and heart failure. It also examines who should not take the drug, other risks, and alternative help for obesity. What is phentermine? Share on Pinterest Lucas Ottone/Stocksy Phentermine is a brain and spinal cord stimulant medication. It can suppress a person’s appetite, making it popular as a weight loss drug. In 1959 , phentermine first came onto the market as part of a combination obesity drug. Then, in the 1980s , researchers discovered that phentermine and fenfluramine — another appetite suppressant — had a synergistic effect when a person took them together. This means their combined effect was greater than the sum of their two separate effects. At this time, the combination drug “fen-phen” became a mainstay of obesity treatment. However, fen-phen had a strong link to pulmonary hypertension and valvular heart disease. Researchers also discovered a link between fenfluramine alone and these two conditions. Consequently, the Food and Drug Administration (FDA) banned fenfluramine in 1997, but it continues to allow the short-term use of phentermine. Can phentermine cause heart failure? Sometimes, doctors prescribe phentermine alone. Alternatively, they prescribe a combination drug containing topiramate, an antiseizure drug. The possibility of heart failure differs when taking phentermine alone and taking the combination drug. Phentermine Experts cannot rule out a link between phentermine alone and heart valve disease. There have been rare reports of the condition manifesting in people who took it. Combination of phentermine and topiramate The combination of phentermine and topiramate may increase resting heart rate up to 20 beats per minute (bpm). This means that a person who normally has a resting heart rate of 75 bpm would have a resting heart rate as high as 95 bpm. Despite this adverse effect, the product label does not mention a risk of heart valve disease, as in phentermine alone. Additionally, the combination of phentermine and topiramate can cause serious interactions with other medications that can affect the heart. For example, when a person takes it with a selective serotonin reuptake inhibitor (SSRI) medication, it may cause serotonin syndrome. This can be very dangerous. Risk factors People with cardiovascular disease have a higher risk of heart side effects, so they should not take phentermine. This includes those with: congestive heart failure
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Read More »liraglutide (Saxenda) or semaglutide (Wegovy), which mimics a hormone that may regulate appetite setmelanotide (Mcivree), which may decrease appetite, boost the feeling of fullness, and increase metabolism However, it is important to note that all of the above have side effects and risks, some of which can be serious. If a person’s doctor thinks they should take an anti-obesity medication, they will prescribe the appropriate medication and dose. Weight loss surgery Weight loss surgery may be an option for people with a body mass index of 35 or higher . It promotes weight loss by making changes in a person’s digestive system. One common type, bariatric surgery, works by dividing the stomach to make a smaller upper pouch. The options have short-term side effects and long-term risks. However, when other weight loss medications and diets have not produced adequate results, doctors may consider surgery. A person needs to stick to a sustainable diet and exercise plan to maintain results.
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