Can phentermine cause a stroke?

“Weight Loss or Brain Loss?”: Long Term Use of Phentermine Possibly Increases Risk for Ischemic Stroke.

shmabstracts.org - Weight Loss or Brain Loss?"": Long Term Use of Phentermine Possibly ...

How long does it take cinnamon to lower blood sugar?

One study showed that consuming 1 gram (g) of cinnamon extract daily for 12 weeks reduced fasting blood sugar levels and improved markers of...

Last updated May 3, 2022

What are the three hormones for weight loss?

The hormones leptin and insulin, sex hormones and growth hormone influence our appetite, metabolism (the rate at which our body burns kilojoules...

Last updated Mar 12, 2020

Promotion

Cherry Onaiwu, M.D.*; Luay Sarsam, M.D. and Carrie Valenta, M.D., Creighton University, Omaha, NE

Abstract Number: 717

Case Presentation: A 39 y/o female with no significant past medical history and long term use of phentermine for weight loss presented to our hospital with complaints of transient right sided weakness and right sided facial droop lasting 30 min. At time of presentation, her symptoms had resolved completely and review of systems and physical exam were unremarkable with no focal deficits. Stroke team was consulted and patient was given full dose Aspirin (ASA), high intensity statin, and plavix. Imaging studies including CT head, MRA head and neck, MRI brain were unremarkable and TTE with bubble study was normal. CBC, CMP, and lipid profile were normal. She was diagnosed with TIA and remained asymptomatic and was discharged home with instructions to continue ASA, plavix, and atorvastatin and follow up with neurology outpatient. The next day, she presented again after waking up with expressive aphasia and right sided weakness. Vital signs were stable and physical exam was remarkable for dysarthria, decreased strength in right upper and lower extremities, and NIHSS of 4. Repeat imagining was ordered and MRI Brain on this occasion showed 2cm linear focus of acute ischemia within medial left basal ganglia and pt was diagnosed with ischemic stroke and per neurology was not a candidate for tpa. All other studies including MRA head and neck, venous lower extremity dopplers, and hypercoagulable work up were negative. She was given therapeutic lovenox, ASA, plavix, and lipitor and over the course of the next few days she clinically improved with resolution of expressive aphasia and improved right upper extremity weakness. She was discharged home with physical therapy, neurology follow up, and lipitor, ASA, and apixaban with instructions to stop smoking, avoid OCPs, and discontinue phentermine. Her past medical history is only significant for headaches associated with her menstrual periods which resolve with use of PRN advil. She used no medications apart from the phentermine. She has a 2.5 pack year smoking history and drinks alcohol occasionally. She denied any history of clotting disorders, miscarriage, and does not use OCPs. She denied use of illicit drugs. Her family history was only significant for hypertension in her father and mother. She was using phentermine dialy for weight loss as prescribed by her PCP for a period of 2 years prior to presentation Discussion: Phentermine is a psychostimulant and anorexiant, structurally similar to amphetamines, used medically as an appetite suppressant. It is most commonly known for it’s use with fenfluramine (fen-phen) which was pulled from the market due to significant cardiac adverse events. There are limited efficacy and safety data for phentermine and it’s approval for the management of obesity is limited to short-term use (≤12 weeks). A literature search only produced two case reports (from 1993) demonstrating possible association of phentermine use with ischemic stroke and ischemic colitis. To our knowledge there are no studies to date evaluating the risk of ischemic events with it’s long term use. Conclusions: With the evergrowing popularity of weight loss drugs, it is imperative to evaluate the long term effects of this FDA approved drug. Our relatively young patient had very few risk factors for ischemic stroke. Amphetamine use has been associated with ischemic stroke due to it’s vasoconstrictive properties so randomized controlled trials evaluating the relationship between the pharmacologically similar phentermine for ischemic stroke are needed.

What is class 4 obesity?

Obesity by BMI can be further stratified into class I (30-34.9), class II (35-39.9), class III (≥40), class IV (≥50), and class V (≥60). Jan 4, 2018

Last updated Dec 14, 2022

How can I cut my weight to look ripped?

The rest from here is really just supplemental to those two key factors. Step 3: Eat Enough Protein. ... Step 4: Eat a Moderate Amount of Healthy...

Last updated Jul 7, 2021

Promotion

What is the name of the drug for weight loss?

Phentermine and topiramate (Qsymia) Topiramate causes weight loss in several ways, including helping you feel full, making foods taste less appealing, and burning more calories. Approved for long-term use? Yes. Qsymia has much lower amounts of phentermine and topiramate than when these drugs are given alone.

webmd.com - Diet Pills, Prescription Weight Loss Drugs, Appetite Suppressants

Eating less and moving more are the basics of weight loss that lasts. For those who are considered obese, prescription weight loss drugs are now considered a frontline treatment. You are considered obese if your body mass index (BMI) is 30 or higher. Doctors will prescribe them if you meet this criterion or if it's at least 27 and you have a condition that may be related to your weight, like type 2 diabetes or high blood pressure. You'll still need to focus on diet and exercise while taking these drugs, and they're not for everyone. The medication semaglutide (Wegovy) received FDA approval for treatment of obesity in 2021. More common prescription weight loss drugs which have been in use longer include: liraglutide (Saxenda), naltrexone-bupropion (Contrave), orlistat (Alli, Xenical), phentermine-topiramate (Qsymia ), and tirzepatide (Mounjaro). Before you get a weight loss drug prescription, tell your doctor about your medical history. That includes any allergies or other conditions you have; medicines or supplements you take (even if they're herbal or natural); and whether you're pregnant, breastfeeding, or planning to get pregnant soon.

What foods are good to eat at night?

Savory Late-Night Snacks Popcorn. When winding down before bed with a bag of popcorn and a show, you may wonder, is popcorn a good late-night...

Last updated Apr 19, 2022

What is the average size of a woman 2022?

The average American woman 20 years old and up weighs 170.6 pounds and stands at 63.7 inches (almost 5 feet, 4 inches) tall. And the average waist...

Last updated Nov 30, 2019

Promotion

How do I get a super slim stomach?

Techniques that may help people get a flat stomach include: Add cardio. Share on Pinterest Running is effective in trimming a person's midsection....

Last updated Sep 21, 2022

Learn More »

Promotion

What medications causes rapid weight loss?

Six weight-loss drugs have been approved by the U.S. Food and Drug Administration (FDA) for long-term use: Bupropion-naltrexone (Contrave)...

Last updated Dec 12, 2019